Dental Research Journal

REVIEW ARTICLE
Year
: 2016  |  Volume : 13  |  Issue : 5  |  Page : 379--386

Scaffolds in regenerative endodontics: A review


Kinjal M Gathani, Srinidhi Surya Raghavendra 
 Department of Conservative Dentistry and Endodontics, Sinhgad Dental College and Hospital, Pune, Maharashtra, India

Correspondence Address:
Srinidhi Surya Raghavendra
Department of Conservative Dentistry and Endodontics, Sinhgad Dental College and Hospital, Pune, Maharashtra
India

Root canal therapy has enabled us to save numerous teeth over the years. The most desired outcome of endodontic treatment would be when diseased or nonvital pulp is replaced with healthy pulp tissue that would revitalize the teeth through regenerative endodontics. «SQ»A search was conducted using the Pubmed and MEDLINE databases for articles with the criteria «SQ»Platelet rich plasma«SQ», «SQ»Platelet rich fibrin«SQ», «SQ»Stem cells«SQ», «SQ»Natural and artificial scaffolds«SQ» from 1982-2015«SQ». Tissues are organized as three-dimensional structures, and appropriate scaffolding is necessary to provide a spatially correct position of cell location and regulate differentiation, proliferation, or metabolism of the stem cells. Extracellular matrix molecules control the differentiation of stem cells, and an appropriate scaffold might selectively bind and localize cells, contain growth factors, and undergo biodegradation over time. Different scaffolds facilitate the regeneration of different tissues. To ensure a successful regenerative procedure, it is essential to have a thorough and precise knowledge about the suitable scaffold for the required tissue. This article gives a review on the different scaffolds providing an insight into the new developmental approaches on the horizon.


How to cite this article:
Gathani KM, Raghavendra SS. Scaffolds in regenerative endodontics: A review.Dent Res J 2016;13:379-386


How to cite this URL:
Gathani KM, Raghavendra SS. Scaffolds in regenerative endodontics: A review. Dent Res J [serial online] 2016 [cited 2019 Jun 17 ];13:379-386
Available from: http://www.drjjournal.net/article.asp?issn=1735-3327;year=2016;volume=13;issue=5;spage=379;epage=386;aulast=Gathani;type=0