Dental Research Journal

ORIGINAL ARTICLE
Year
: 2018  |  Volume : 15  |  Issue : 5  |  Page : 327--333

Effect of Sudarshan Kriya Pranayama on periodontal status and human salivary beta-defensin-2: An interventional study


R Ananthalakshmi1, Jaideep Mahendra2, P Jayamathi3, Little Mahendra4, Nashra Kareem2, S Subramaniam5 
1 Department of Oral Pathology and Microbiology, Thai Moogambigai Dental College and Hospital, Chennai, Tamil Nadu, India
2 Department of Periodontology, Meenakshi Ammal Dental College and Hospital, Chennai, Tamil Nadu, India
3 Department of Biochemistry, Meenakshi Ammal Dental College and Hospital, Chennai, Tamil Nadu, India
4 Department of Periodontology, Priyadharshini Dental College and Hospital, Tamil Nadu Dr. MGR University, Chennai, Tamil Nadu, India
5 Regenix Research Centre, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Jaideep Mahendra
Department of Periodontology, Meenakshi Ammal Dental College and Hospital, Chennai, Tamil Nadu
India

Background: Yogic stretching (asana) has been proven to have an effect on salivary human beta-defensin-2 (HBD-2) concentration, which is an antimicrobial peptide and is an inflammatory marker in periodontal disease. Sudarshan Kriya Pranayama (SKP) is a part of yoga which involves rhythmic breathing. Hence, we aim to evaluate the periodontal parameters and to estimate the salivary HBD-2 level before and after SKP program in periodontitis individuals. Materials and Methods: An interventional study was designed and individuals were divided into three groups: Group I – healthy periodontium, Group II – chronic gingivitis, and Group III – chronic periodontitis. SKP was the interventional tool. The clinical parameters such as plaque index (PI), gingival index (GI), probing pocket depth (PPD), clinical attachment level (CAL), and salivary HBD-2 level were analyzed at baseline and 90 days after the SKP practice. Enzyme-linked immunosorbent assay (ELISA) was used to evaluate salivary HBD-2. McNemar's Chi-square, Paired samples t-test, and one-way ANOVA were used to analyze the results. P < 0.05 was considered statistically significant. Results: Following the SKP intervention, the clinical parameters such as PI and GI improved significantly in all the groups (P < 0.001); however, Group III showed a significant reduction as compared to the other groups. The mean baseline salivary HBD-2 levels of Group I, Group II, and Group III were 91.78 ng/μl, 110.22 ng/μl, and 157.63 ng/μl which was further decreased to 95.22 ng/μl, 98.22 ng/μl, and 132.88 ng/μl, respectively, following SKP intervention (P < 0.001). However, Group III had a higher HBD-2 level at 90th day as compared to other groups. Conclusion: There was an improvement in PI and GI with a decrease in salivary HBD-2 in chronic periodontitis patients following SKP. Hence, SKP can be considered as an adjunct to treatment modality in patients with periodontal disease.


How to cite this article:
Ananthalakshmi R, Mahendra J, Jayamathi P, Mahendra L, Kareem N, Subramaniam S. Effect of Sudarshan Kriya Pranayama on periodontal status and human salivary beta-defensin-2: An interventional study.Dent Res J 2018;15:327-333


How to cite this URL:
Ananthalakshmi R, Mahendra J, Jayamathi P, Mahendra L, Kareem N, Subramaniam S. Effect of Sudarshan Kriya Pranayama on periodontal status and human salivary beta-defensin-2: An interventional study. Dent Res J [serial online] 2018 [cited 2020 Oct 26 ];15:327-333
Available from: https://www.drjjournal.net/article.asp?issn=1735-3327;year=2018;volume=15;issue=5;spage=327;epage=333;aulast=Ananthalakshmi;type=0